Tr-fret fxr coactivator assay
WebThe FXR (Farnesoid X Receptor) Agonist Assay Kit (TR-FRET) is designed to measure binding of the FXR and SRC-1 (Steroid Receptor Coactivator 1) for screening FXR agonists … WebKit-0977. Description : The TR-FRET FXR (farnesoid X receptor) Coactivator Assay Kit provides a sensitive and robust method for high-throughput screening of potential FXR …
Tr-fret fxr coactivator assay
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WebHomogeneous Time-Resolved Fluorescence (HTRF) . HTRF is a versatile TR-FRET technology developed by Cisbio for detecting biomolecular interactions. A typical HTRF assay uses a europium cryptate as the donor, and the organic fluorophore d2 as the acceptor. The donor and acceptor can be used to label a variety of biomolecules, for … WebTR- FRET formats [ 9 , 10 ]. A simpliÞ ed version of FXR TR-FRET coactivator recruitment assay is developed using a ß uorescein- labeled coactivator peptide [ 6 ]. Some of the FXR assays are opti-mized in 96-, 384-, or 1536-well formats and used for compound screening. Here we describe a high-throughput screening approach to
WebNov 3, 2024 · When running the LanthaScreen™ TR-FRET FXR coactivator assay in agonist mode, FXR-LBD is added to ligand test compounds followed by addition of a mixture of … WebThe LanthaScreen™ TR-FRET FXR Coactivator Assay Kit contains FXR-LBD (GST) protein, fluorescently labeled SRC2-2 coactivator peptide, Tb-labeled anti-GST antibody, and …
WebMar 28, 2024 · LanthaScreen™ TR-FRET FXR Coactivator Assay Kit, 800 x 20μL Assays, Green, 384-Well Plate Format, Tb (Terbium) Dye Type, Fluorescent Detection Method, TR-FRET Technique, For Pharma & Biopharma, Target & Lead Identification & Validation: For Use With (Equipment) Microplate reader: Quantity: 800 x 20 μL Assays: Content And … WebThe LanthaScreen TR-FRET FXR (farnesoid X receptor) Coactivator Assay Kit provides a sensitive and robust method for high-throughput screening of potential FXR ligands as agonists of coactivator recruitment. The kit uses a terbium (Tb)-labeled
WebCatalog number: A15140. The LanthaScreen™ TR-FRET FXR (farnesoid X receptor) Coactivator Assay Kit provides a sensitive and robust method for high-throughput …
WebThe performance of each lot of FXR, LBD (GST) is confirmed in the following assay(s): LanthaScreen™ TR-FRET FXR Coactivator Assay (PV4833). The ligand GW4064 was … constituency\u0027s w6WebFederal Contract Opportunity for Goat Assay Kits HHS-NIH-NIDA-SSSA-NOI-15-718. The NAICS Category is 325413 - In-Vitro Diagnostic Substance Manufacturing. Posted Aug 11, 2015. Due Aug 26, 2015. Posted by the National Institutes of Health (HHS). The work will be performed at 9800 Medical Center Dr, Rockville, MD 20850, USA ed sheeran / elton johnWebThe LanthaScreen™ TR-FRET FXR (farnesoid X receptor) Coactivator Assay Kit provides a sensitive and robust method for high-throughput screening of potential FXR ligands Invitrogen™ LanthaScreen™ TR-FRET FXR Coactivator Assay Kit, goat Fisher Scientific ed sheeran e beyoncé perfected sheeran e harry stylesWebBile acids are cholesterol-derived metabolites with a well-established role in the digestion and absorption of dietary fat. More recently, the discovery of bile acids as natural ligands for the nuclear farnesoid X receptor (FXR) and membrane Takeda G-protein-coupled receptor 5 (TGR5), and the recognition of the effects of FXR and TGR5 signaling have led to a … constituency\u0027s wdWebThe LanthaScreen™ TR-FRET Androgen Receptor Coactivator Assay Kit provides a sensitive and robust method for high-throughput screening of potential androgen receptor (AR) … constituency\u0027s w8WebInvitrogen • LanthaScreen™ TR-FRET Liver X Receptor beta Coactivator Assay Page 2 of 11 1. KIT CONTENTS The LanthaScreen™ TR-FRET Liver X Receptor beta Coactivator Assay, … constituency\u0027s wh