Web6 jul. 2012 · Consequently, MIF-deficient [MIF-knock-out (KO)] pancreatic islets or islet cells showed significant resistance to cytokine-induced death than those isolated from … Serum macrophage migration inhibitory factor (MIF) was reported to be correlated with severity of acute pancreatitis (AP) based on the 1992 Atlanta classification. However, MIF has never been proven to be predictive of disease severity based on the revised Atlanta classification (RAC). Meer weergeven This study was conducted according to the guidelines laid down in the Declaration of Helsinki and all procedures involving human subjects were approved by the Ethics … Meer weergeven Peripheral venous blood samples were obtained immediately on admission (within 48 h of onset of symptom) of each patient and each healthy volunteer. Plasma used for testing MIF was obtained after centrifugation … Meer weergeven The diagnosis and classification of AP were based on the RAC and AGA guideline [1, 3]. The criteria for organ failure (OF) was defined for 3 organ systems (respiratory, cardiovascular, or renal) on the … Meer weergeven Serum MIF concentration was measured by a quantitative sandwich enzyme linked immunosorbent assay (ELISA) (R&D Systems, Minneapolis, MN, USA) following the recommended protocols in the supplemental … Meer weergeven

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Web18 mei 2015 · Importantly, we demonstrate that MIF is elevated in plasma exosomes isolated from a mouse model of pancreatic cancer (PKCY mice) bearing either pancreatic intraepithelial neoplasia (PanIN) or PDAC ... Web18 mei 2015 · Macrophage migration inhibitory factor (MIF) can promote the formation of fibrotic environments at distal sites. High levels of exosomal MIF in patients with stage I pancreatic cancer has... corus stock range and specifications

Pancreatitis and associated lung injury: When MIF miffs

Web23 dec. 2024 · INTRODUCTION. Obesity is considered one of the biggest concerns and a main cause of morbidity and mortality in the Arabian Gulf region and worldwide [1, 2].The … Web1 mei 2010 · Background. Pancreatic ductal adenocarcinoma (PDAC) is the eighth most common cancer with the lowest overall 5-y relative survival rate. Gene expression profiling of PDAC revealed an overexpression of the macrophage migration inhibitory factor (MIF), a lymphokine involved in cell-mediated immunity and inflammation, as well as in the … Web1 feb. 2007 · Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine that is released by macrophages and lymphocytes and plays an important pathogenetic role … corus stock price globe and mail