Ifn alpha2
WebInterferons-alpha (IFN-alpha) are pleiotropic cytokines belonging to type I IFNs, extensively used in the treatment of patients with some types of cancer and viral disease. IFN-alpha … Webifn-γ的产生受抗原呈递细胞分泌的细胞因子控制，尤其是il12和il18。 IFN-γ通过其受体IFNGR1和IFNGR2发出信号，激活巨噬细胞并促进Th1反应。 IFN-γ信号是肉芽肿形成 …
Ifn alpha2
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WebIFN alpha (Interferon alpha) is a Type I interferon belonging to a family of structurally related, species-specific proteins exclusive to vertebrates. The interaction of IFN-alpha … WebInterferon-alpha 2/ IFNα 2 is a cytokine secreted in response to viral infection. IFNα 2 stimulates cellular gene expression that prevents viral spread and replication. IFNα 2 is a …
WebThe Human IFN alpha Matched Antibody Pair Kit comes with pre-matched antibody pairs, standards, and streptavidin-HRP to develop your own enzyme linked immunosorbent assays (ELISA) to detect and quantify protein levels of human IFN alpha. Buffer reagents and microplates needed to complete the ELISA reaction are sold separately. WebView our 49 IFN-alpha products for your research including IFN-alpha Primary Antibodies, Proteins and Enzymes, ELISAs, Simple Plex Assays, Luminex ... Control for use with Human IFN-alpha and Human IFN-alpha 2/IFNA2 Simple Plex Cartridge Kitss . 899050. 1 Image. Ctrl. Show Size & Price. Recombinant Cotton Rat IFN-alpha (Cys109Tyr) Protein ...
Web31 mrt. 2024 · The promoter of the gene encoding a cytoplasmic guanylate-binding protein (GBP) contains two overlapping elements: the interferon stimulation response element (ISRE), which mediates alpha interferon (IFN-α)-dependent transcription, and the IFN-γ activation site (GAS), which is required for IFN-γ-mediated stimulation. WebIFN-alpha subtypes are well described (5-9). There are 15 human IFN-alpha subtypes with 80% amino acid identity (10). The number of IFN-alpha subtypes varies by species with 6 equine subtypes, 17 porcine subtypes, 14 bovine subtypes, and 9 canine subtypes known currently. Human IFN-alpha subtypes include: IFN-alpha 1a, IFN-alpha 1b, IFN-alpha ...
WebIFN-alpha is a cytokine that has an immunomodulatory function. It plays an important role not only in antiviral activity but also in several physiologic functions, such as activation of …
WebInterferons (IFN) are a family of cytokines with potent antiviral, antiproliferative and immunomodulatory properties, classified based on their binding specificity to cell surface … employee health fitness challengeWebOverall, IFN-α has a general inflammatory action which skews the immune response towards a Th1 profile. Subtype α2 increases the expression of HLA-I molecules, which … draw and label the teethThere are 3 types of IFNs: Interferon type I, Interferon type II and Interferon type III. The type II IFN, also called IFNγ, is produced by specific cells of the immune system. Unlike type I and type III IFNs, IFNγ has only a modest role in directly restricting viral infections. Type I and type III IFNs act similarly. Meer weergeven Interferon alpha-2 is a protein that in humans is encoded by the IFNA2 gene. Meer weergeven Human interferon alpha-2 (IFNα2) is a cytokine belonging to the family of type I IFNs. IFNα2 is a protein secreted by cells infected by a Meer weergeven When a cell is infected by a virus, some components of the virus, mainly viral nucleic acids, are recognized by specialized … Meer weergeven Induced IFNα2 is secreted by the infected cells and acts locally as well as systemically on cells expressing a specific cell surface receptor able to bind type I IFNs. The … Meer weergeven If given orally, IFNα2 is degraded by digestive enzymes and is no longer active. Thus, IFNα2 is mainly administrated by injection essentially subcutaneous or intramuscular. … Meer weergeven The gene encoding IFNα2, the IFNA2 gene, is clustered with all other type I IFN genes on chromosome 9 and as all type I IFN genes, it is devoid of intron. The open reading frame (coding sequence) of IFNA2 codes for a pre-protein of 188 amino acids with a 23 … Meer weergeven The broad spectrum of ISGs explains the wide range of biological activity of type I IFNs. In addition to their antiviral activity, type I IFNs also inhibit the proliferation of cells and regulate the activation of the immune system. Type I IFNs … Meer weergeven employee health gcmcWebSpecifications Recombinant human IFN-α2b. Source: Mammalian; Chinese hamster ovary (CHO) cells Uniprot ID: P01563 Alternate name: IFN-alpha 2 Formulation: Lyophilized from a 0.2 µm filtered phosphate buffer solution (pH 7.4) containing 2% human serum albumin (HSA) and 5% saccharose. Molecular mass: ~ 21 kDa (SDS-PAGE) Solubility: 100 μg/ml … draw and label the parts of volcanoWeb30 jan. 2001 · Polypeptide drugs are generally short-lived species in circulation. In this study, we have covalently linked seven moieties of 2-sulfo-9-fluorenylmethoxycarbonyl (FMS) to the amino groups of human interferon-alpha2. The derivative thus obtained (FMS(7)-IFN-alpha2) has approximately 4% the biological … draw and label the structure of the earthWebNational Center for Biotechnology Information. 8600 Rockville Pike, Bethesda, MD, 20894 USA. Contact. Policies. FOIA. HHS Vulnerability Disclosure. National Library of … drawandlyricsWebIFN-alpha 2/IFNA2: Products. Interferon-alpha (IFN-alpha), also known as leukocyte interferon, represents a group of related but distinct proteins that share over 95% amino acid sequence homology. They are members of … employee health hennepin healthcare